在今天的E3展前新闻发布会上，任天堂公布了首批第一方和第三方Wii主机游戏，共计70余款。
在任天堂自家游戏中，暂定名《Super Mario Galaxy》的新超级马里奥应该足以让玩家们兴奋不已，而《The Legend of Zelda: Twilight Princess》(塞尔达传说：黎明公主)将会称为Wii首发游戏与主机同步登场，并会在同日发布GameCube版。
其它经典游戏包括《Metroid Prime 3: Corruption》、《Fire Emblem》、《WarioWare: Smooth Moves》等，首次公布的新开发游戏则有动作游戏《Disaster: Day of Crisis》、赛车游戏《Excite Truck》、动作冒险游戏《Project H.A.M.M.E.R.》、体育游戏《Wii Sports》等等。
任天堂还表示，明天E3正式开幕之后，将会有27款第一方和第三方Wii游戏进行展示，并且都是可玩儿的。
以下是任天堂列出的第三方Wii游戏名单：
Activision
-Tony Hawk's Downhill Jam
-Marvel: Ultimate Alliance
-Call of Duty 3
AQ Interactive
-Boxing Action (currently untitled)
Atari
-Dragon Ball Z Budokai: Tenkaichi 2
Atlus
-Trauma Center: Second Opinion
Banpresto
-Family Action Game (currently untitled)
Buena Vista Games
-Disney's Chicken Little: Ace in Action
-Disney's Meet the Robinsons
Capcom
-Resident Evil game
D3Publisher
-SIMPLE series
-Original Action Game (currently untitled)
Eidos
-Title TBD
Electronic Arts
-Madden NFL '07
-Medal of Honor Airborne
Epoch
-Title TBD
From Software
-Action game (currently untitled)
Genki
-Title TBD
Hudson Soft
-Bomberman Land
-Flight Game (currently untitled)
Jaleco
-Title TBD
Koei
-Sengoku Action
Konami Digital Entertainment
-Elebits
-Soccer Game (currently untitled)
Majesco
-Bust-A-Move Revolution
Marvelous Interactive
-Bokujo Monogatari ("Ranch Story")
-Heroes
-Kawa no Nushitsuri
-Original simulation game (currently untitled)
Mastiff
-Mr. D. Goes to Town (working title)
Midway Games
-The Ant Bully
-Happy Feet
Milestone
-New Vertical Scrolling Shooting Game
-New Action Game
MTO
-Character Action Game (currently untitled)
-SAN-X All-Star Revolution
Namco Bandai Games
-Final Furlong
-Mobile Suit Gundam
-SD Gundam G Breaker
-Digimon
-One Piece Unlimited Adventure
-New Action Game (currently untitled)
-New RPG (currently untitled)
-Tamagotchi
-Title TBD
Natsume (developed by Marvelous)
-Harvest Moon
Sega
-Super Monkey Ball Banana Blitz
-Sonic Wild Fire
SNK
-Metal Slug Anthology
Spike
-Necro-Nesia
-Jawa
Square Enix
-Codename: Final Fantasy Crystal Chronicles: Crystal Bearers
-Dragon Quest Swords: The Masked Queen and the Tower of Mirrors
Taito
-Turn IT Around!!
-Let's go by train!
-Cooking Mama--Cooking with International Friends
Tecmo
-Super Swing Golf PANGYA
The Game Factory
-Title TBD
THQ
-Avatar: the Last Airbender
-SpongeBob SquarePants: Creature from the Krusty Krab
-Disney/Pixar Cars
Tomy
-Action Game (currently untitled)
-Battle Action (currently untitled)
Ubisoft
-Open Season
-Rayman Raving Rabbids
-Red Steel
Vivendi Universal Games
-Title TBD
Warner Bros. Interactive Entertainment
-Title TBD
